Early Metabolic Changes Following Focal Traumatic Brain Injury in Rats Measured Using H MRS
نویسندگان
چکیده
S. Xu, S. Roys, J. Racz, D. Shi, J. Zhuo, R. Gullapalli, and G. Fiskum Core for Translational Research in Imaging @ Maryland (C-TRIM), University of Maryland School of Medicine, Baltimore, MD, United States, Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD, United States, Anesthesiology and the Center for Shock Trauma and Anesthesiology Research, University of Maryland School of Medicine, Baltimore, MD, United States
منابع مشابه
Early microstructural and metabolic changes following controlled cortical impact injury in rat: a magnetic resonance imaging and spectroscopy study.
Understanding tissue alterations at an early stage following traumatic brain injury (TBI) is critical for injury management and limiting severe consequences from secondary injury. We investigated the early microstructural and metabolic profiles using in vivo diffusion tensor imaging (DTI) and proton magnetic resonance spectroscopy ((1)H MRS) at 2 and 4 h following a controlled cortical impact i...
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Specific neurochemicals measured with proton magnetic resonance spectroscopy ((1)H-MRS) may serve as biomarkers of pathological mechanism in the brain. We used high field in vivo (1)H-MRS to measure a detailed neurochemical profile after experimental traumatic brain injury (TBI) in rats. We characterized neurochemical changes in the contused cortex and the normal-appearing perilesional hippocam...
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